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2 edition of quantitative study of the effect of strain redistribution on bone remodelling. found in the catalog.

quantitative study of the effect of strain redistribution on bone remodelling.

John Anthony Szivek

quantitative study of the effect of strain redistribution on bone remodelling.

by John Anthony Szivek

  • 307 Want to read
  • 24 Currently reading

Published .
Written in English


The Physical Object
Pagination248 leaves
Number of Pages248
ID Numbers
Open LibraryOL14748205M

Lanyon and Rubin showed that the strain rate has also an effect on bone remodelling and recent BRMs have included this effect. As established in the mechanostat theory [ 10 ], bone is resorbed from sites where it is in disuse (low mechanical stimulus) and is deposited where the loads are frequent and intense (high mechanical stimulus). Abstract. This study investigates the relationship between microdamage and bone adaptation in a sheep forelimb model. Based on gait analysis, a simple test rig was developed for in vitro measurement of strain on the cranial and caudal surfaces of the radius to study the effects of ulnar osteotomy and ulnar reinforcement using a Steinmann pin.

However the initial remodelling of primary bone to produce Haversian bone results in a reduction in strength (4). As for the influence of the rate of loading on bone remodelling, there is good evidence to suggest that intermittent deformation can produce a marked adaptive response in bone, whereas static deformation has little effect (). Animals. The mouse has become the animal of choice for investigating bones' adaptive responses to loading, 13 and the C57BL/6 strain has been extensively used as the background of genetically modified animals in the field of bone research. In the present study, virgin female C57BL/6 mice were purchased from Charles River Laboratories, Inc. (Margate, UK) at 16 weeks of age, and housed in cages.

The effects of biophysical force on bone remodelling have become increasingly evident in recent years. It is well known that extended periods of immobilisation lead to bone loss. This is especially apparent in situations of weightlessness. Subjects exposed to weightlessness have shown diminished or arrested bone formation (1), reduced collagen. Abstract. In silico modeling is a powerful tool for the prediction of bone remodeling and mechanobiology. As the method is gaining popularity a standardized measure for the in vivo validation of the quality of the produced simulations is required. In this review, we discuss current validity assessment approaches, as well as the validation ‘gold standard’, in which the experimental and.


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Quantitative study of the effect of strain redistribution on bone remodelling by John Anthony Szivek Download PDF EPUB FB2

Principle for the FE calculation of strain-adaptive bone remodelling. Within this study, the strain-adaptive bone remodelling in the periprosthetic femur was computed by means of the FE solver (re Corporation, Santa Ana, USA) Cited by: In the translated bones remodelling occurs in a direction generally opposite to the direction of movement but this is modified by the influence of soft tissue tension and pressure.

Bone resorbs on the outer leading side under continuous pressure and forms on Cited by: 2. The effect of this axial strain was far less marked than that of strain rate, however, and only increased the percentage of the total variance which could be explained by between 6 and 12%.

The direction of bending and axial loading (tension or compression) appeared to have no effect on the course of the remodelling by:   Introduction.

Bone is a unique material in its ability to adapt its mass and structure in response to the loads to which it is exposed.The loads induce strains in the bone, and the modeling and remodeling stimulus has been found to be dependent on strain magnitude, strain frequency, and strain bone mass can either be maintained by a relatively small number of loading cycles Cited by:   The bone remodelling algorithm implemented in this work aims to study the response of bone tissue in the presence of an external mechanical stimulus.

Therefore, the fundamental principle of this model consists on varying the local density of bone according to stress/strain by: 5. His research topic was a study of the nature of activity induced bone formation and the study of bone loss around orthopedic implants.

Structural and functional assessment of intense therapeutic ultrasound effects on partial J. (, Septmeber). A Quantitative Study of the Effect of Strain Redistribution on Bone Remodelling. Thesis. Folia Mo Hert, J., Pribylova, E. and Liskova, M. () Reaction of bone to mechanical stimuli. Part 3.

Microstructure of compact bone of rabbit tibia after intermittent loading. Acta anat. 82, Howell, J. () An experimental study of the effect of stress and strain on bone development.

Anat. Rec. 13, Simulated bone models using acrylic resins have been successfully used to study the effect of load direction at the bone-implant interface. [13] Acrylic resin can be considered as a suitable.

Peak strain at the midshaft of the ulna during wing flapping in the intact bone was recorded from bone bonded strain gauges in vivo as with a maximum rate of change of strain of s   Strain is the key intermediate variable between loading forces and bone remodelling.

Animal studies have shown that static loading of bone has no osteogenic effect; bone loss occurs as if there were no loading at all. Dissertation: A Quantitative Study of the Effect of Strain Redistribution.

on Bone Remodelling. Advisor: Drs. Robert M. Pilliar and George C. Weatherly. Degree Awarded: Master of Applied Science, Dept Metallurgy and Material Science.

University of Toronto, Toronto, Ontario, Canada. Thesis Topic: Stress Redistribution and Bone. Effect of swimming on bone architecture The results of this study indicate that swimming training in growing rats increases their bone strength. Swimming activity seems to provide mechanical stimuli of sufficient intensity and diversity to induce an increase in bone tissue and its redistribution within the bone cross-section.

There are several numerical investigations on bone remodelling after total hip arthroplasty (THA) on the basis of the finite element analysis (FEA). For such computations certain boundary conditions have to be defined. The authors chose a maximum of three static load situations, usually taken from the gait cycle because this is the most frequent dynamic activity of a patient after.

The mechanical effect of subchondral stiffening on the surrounding trabecular bone is poorly understood. This study employs a relatively new application of digital image correlation to measure. In this study we attempt a “local” correlation between bone remodelling occurred after total hip arthroplasty and the strain alterations induced by the cementless prosthesis.

To determine these alterations we used both experimental and computer aided simulation approaches. The effect of implant-bone bonding and the effect of implant surface roughness on bone remodeling near the bone-implant interface were studied by using a surface remodeling theory and the boundary.

The interface between the bone and strain gauge sensing surface consisted of layers of polysulfone, polysulfone/CPC, and CPC/bone. Parameter studies examined the effect of interface thickness and modulus, gauge geometry, partial gauge debonding, and waterproofing on the strain transfer from the bone to the gauge sensing element.

effects of mechanical stimuli and bone geometry on bone remodelling (Bronner and Worrell, ), can be studied simultaneously.

In our 2 nd modification on the adaptive elasticity theory, we used. J Sports Sci. Summer;5(2) Bone dynamics: stress, strain and fracture. Martin AD(1), McCulloch RG. Author information: (1)Sport and Exercise Sciences Research Institute, University of Manitoba, Winnipeg, Canada.

Bone is a dynamic tissue whose functional mass is controlled by the balance between the endocrine drive towards bone resorption and the mechanically-engendered drive.

Mechanical regulation of bone remodelling. Mechanical force is a key regulator of bone remodelling and of bone architecture in general (Jacobs et al., ). It influences bone metabolism not only locally (e.g.

resulting in a bigger bone in the serving arm of a professional tennis player), but also systemically (as illustrated by the profound.

Mechanical strain causes bone remodelling when it exceeds threshold levels of a proposed ‘lazy zone’, in which bone density is unresponsive to mechanical strain. Here .Constitutive models for bone remodeling are established from micromechanical analyses at the scale of individual trabeculae defining the representative unit cell (RUC), accounting for both first- and second-order deformation gradients.

On the microscale, trabeculae undergo apposition of new bone modeled by a surface growth velocity field driven by a mechanical stimulus identified to the. BASIC SCIENCE SUMMARY Bone strength and “mass”: Physical determinants and relationships.

Bone's “material properties” partly determine its strength. 6 They include its stiffness, ultimate strength, yield point, and true density. However, they change little with age, gender, species, and most diseases compared with the “mass” and architectural contributions described next.